Asthalin: Fast-Acting Relief for Acute Bronchospasm

Asthalin

Asthalin

Asthalin belongs to a group of medicines called fast-acting bronchodilators or “relievers”. It’s used to treat the symptoms of asthma and chronic obstructive pulmonary diseases (COPD) such as coughing, wheezing, and breathlessness.
Product dosage: 100mcg
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Synonyms

Asthalin (salbutamol sulfate) is a rapid-onset, short-acting beta-2 adrenergic agonist (SABA) bronchodilator indicated for the treatment and prevention of bronchospasm in reversible obstructive airway diseases, including asthma and chronic obstructive pulmonary disease (COPD). As a first-line rescue medication, it works by selectively relaxing smooth muscle in the airways, facilitating improved airflow within minutes of administration. Available in multiple formulations—metered-dose inhaler (MDI), dry powder inhaler (DPI), nebulizer solution, and tablets—Asthalin offers flexibility in acute and maintenance therapy, making it a cornerstone in respiratory management protocols worldwide.

Features

  • Contains salbutamol sulfate USP as the active pharmaceutical ingredient
  • Available as 100 mcg/actuation MDI, 200 mcg DPI, nebulizer solution (1mg/mL, 2.5mg/2.5mL, 5mg/2.5mL), and 2mg/4mg tablets
  • Rapid onset of action: bronchodilation typically begins within 5 minutes
  • Duration of effect: 4 to 6 hours for inhaled forms
  • Portable and user-friendly delivery systems with dose counters (where applicable)
  • HFA-propellant inhalers (CFC-free) with consistent particle size distribution

Benefits

  • Provides rapid symptomatic relief during acute asthma attacks or exercise-induced bronchospasm
  • Improves forced expiratory volume (FEV1) and peak expiratory flow rate (PEFR) metrics
  • Reduces airway resistance and decreases work of breathing
  • Enhances quality of life by allowing normal physical activity and sleep
  • May be used as pre-treatment to prevent bronchoconstriction triggered by allergens or exercise
  • Compatible with most concomitant respiratory medications, including corticosteroids and long-acting bronchodilators

Common use

Asthalin is primarily prescribed for the management of reversible obstructive airway conditions. Its most frequent applications include relief of acute bronchospasm in asthma, prevention of exercise-induced bronchoconstriction (EIB), and symptomatic treatment of COPD exacerbations. It is also used off-label in certain cases of hyperkalemia (due to its potassium-shifting effects) and as a tocolytic agent in preterm labor under strict obstetric supervision. In pediatric populations, it is commonly administered via nebulizer for acute wheezing episodes.

Dosage and direction

Inhaler (MDI/DPI): Adults and children >4 years: 1-2 inhalations every 4-6 hours as needed for relief of acute symptoms. Maximum: 8 inhalations/24 hours.
Nebulizer solution: Adults: 2.5mg (one vial) 3-4 times daily; Children: 0.15mg/kg/dose (minimum 1.25mg, maximum 2.5mg) 3-4 times daily.
Tablets: Adults: 2-4 mg 3-4 times daily; Children 6-12 years: 2 mg 3-4 times daily.
Always shake the inhaler well before use. For MDIs, prime the inhaler if new or unused for >2 weeks. Administer during slow, deep inhalation, hold breath for 10 seconds if possible. Rinse mouth after steroid co-therapy.

Precautions

  • Use with caution in patients with cardiovascular disorders (hypertension, arrhythmias, ischemic heart disease)
  • Monitor serum potassium levels; may cause hypokalemia especially with high doses
  • Paradoxical bronchospasm may occur—discontinue immediately if worsening breathing
  • Not recommended as sole therapy for severe or unstable asthma
  • May increase blood glucose levels; use caution in diabetics
  • Do not exceed recommended dosage; increased use indicates deteriorating asthma control

Contraindications

  • Hypersensitivity to salbutamol or any component of the formulation
  • Tachyarrhythmias
  • Idiopathic hypertrophic subaortic stenosis
  • Severe cardiac disease uncontrolled by medication
  • History of hypersensitivity to sympathomimetic amines

Possible side effect

Most common: tremor (particularly fine hand tremor), headache, tachycardia, palpitations, muscle cramps.
Less common: hypokalemia, hyperglycemia, throat irritation, cough, dizziness.
Rare: paradoxical bronchospasm, angioedema, urticaria, hypotension, chest pain.
These are usually dose-dependent and transient, diminishing with continued therapy.

Drug interaction

  • Beta-blockers (e.g., propranolol) may antagonize bronchodilator effects
  • Concomitant use with other sympathomimetics may increase cardiovascular effects
  • Diuretics or corticosteroids may potentiate hypokalemia
  • MAO inhibitors and tricyclic antidepressants may potentiate cardiovascular effects
  • Inhalational anesthetics may increase risk of ventricular arrhythmias

Missed dose

Asthalin is typically used as needed for symptom relief rather than on a fixed schedule. If using regularly scheduled dosing, take the missed dose as soon as remembered unless it is nearly time for the next dose. Do not double the dose to make up for a missed one.

Overdose

Symptoms may include angina pain, hypertension/hypotension, tachycardia, arrhythmias, nervousness, headache, tremor, dry mouth, palpitations, nausea, dizziness, fatigue, malaise, hypokalemia, hyperglycemia, and seizures.
Treatment is supportive and symptomatic: cardiac monitoring, correction of electrolytes, judicious use of cardioselective beta-blockers (with extreme caution in asthmatics). Dialysis is not effective.

Storage

Store at room temperature (15-30°C). Avoid freezing, direct sunlight, and excessive heat. Do not puncture or incinerate canisters. Keep inhaler with mouthpiece down. For nebulizer solutions, use immediately after opening single-dose vials. Discard any solution that is discolored or contains particles. Keep all medications out of reach of children.

Disclaimer

This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional for diagnosis and individualized treatment recommendations. Do not initiate, discontinue, or modify dosage without physician supervision. Asthalin is a prescription medication and should be used strictly as directed by a licensed medical practitioner.

Reviews

“Asthalin has been a lifesaver during my asthma exacerbations. The MDI provides relief within minutes when I feel an attack coming on. As a pulmonologist, I also prescribe it frequently for my patients with good efficacy.” – Dr. Eleanor R., Respiratory Specialist

“After 15 years of COPD, my rescue inhaler is never far. Asthalin’s consistent performance during acute breathlessness episodes gives me the confidence to maintain daily activities. Minor hand tremors are a small trade-off for breathing normally.” – Marcus T., patient

“Pediatric asthma management relies heavily on quick-relief medications. Asthalin nebulization remains our first choice in emergency settings for rapid symptom control in children. Dose adjustment is straightforward based on weight.” – Pediatric Emergency Team, City General Hospital